Ebrahim Soltani 2010.

Methods	Parallel 4‐group randomized trial, conducted in Iran. Study conducted in Iran during 2007 to 2008.
Participants	200 participants aged 10 ‐ 60 years old, with ASA physical status I to II, undergoing strabismus surgery. Exclusion criteria: nausea or vomiting within 1 week of surgery, local infection near acupoint, symptomatic comorbidities, travel sickness, length of stay in the recovery room more than 2 hours or those receiving any medical therapy before surgery.
Interventions	Group 1: sham acupressure wristbands place inappropriately on the posterior surface of both forearms 30 min before induction of anaesthesia plus saline 1ml IV. Removed wristband 6 hours after surgery (n = 50). Group 2: sham acupressure wristbands place inappropriately on the posterior surface of both forearms 30 min before induction of anaesthesia plus metoclopramide 0.2 mg/kg IV immediately before induction. Removed wristband 6 hours after surgery (n = 50). Group 3: sham acupressure wristbands place inappropriately on the posterior surface of both forearms 30 min before induction of anaesthesia plus ondansetron 0.15 mg/kg IV immediately before induction. Removed wristband 6 hours after surgery (n = 50). Group 4: bilateral wristbands on P6 acupoint 30 min before induction of anaesthesia plus saline 1ml IV. Removed wristband 6 hours after surgery (n = 50).
Outcomes	Nausea (0 ‐ 2 h), Vomiting (0 ‐ 2 h) in recovery room
Notes	Subgroup analysis for adults and children not done as overall population was mixed in age range (10 ‐ 60 years). No incidence for postoperative nausea or vomiting (0 ‐ 24 h) reported. No details about funding source or any declarations of interest among authors.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Insufficient details. "Patients were randomised into four groups using random numbers, with 50 cases in each group."
Allocation concealment (selection bias)	Unclear risk	Insufficient details.
Blinding of patients (performance bias) All outcomes	Low risk	Authors attempted to blind antiemetic drugs use with saline placebo and used sham acupressure wristbands on non‐acupoint.
Blinding of healthcare providers (performance bias) All outcomes	Unclear risk	Wristbands were not covered with dressing. No details about whether healthcare providers were blinded or not.
Blinding of outcome assessor (detection bias) All outcomes	Low risk	Nursing staff recording the PONV were unaware of group allocations.
Incomplete outcome data (attrition bias) All outcomes	Low risk	"No patient was excluded after admission to the study."
Selective reporting (reporting bias)	Low risk	All expected outcomes reported.
Other bias	Low risk	"There was no statistically significant differences with respect to demographic data between groups in the study."