Harmon 2000.

Methods	Parallel‐group randomized trial, conducted in Ireland. Study dates not reported.
Participants	94 healthy women (18 ‐ 40 years) undergoing elective Caesarean section. Exclusion: previous history of PONV, nausea and vomiting in previous 24 hours, obesity (BMI > 35), diabetes mellitus, or previous experience of acupuncture or acupressure.
Interventions	Acupressure on P6 acupoint on right wrist, applied 5 min before administration of spinal anaesthesia, removed just before assessment 6 hours after discharge to the ward (n = 47). Sham acupressure on non‐acupoint site, applied 5 min before administration of spinal anaesthesia, removed just before assessment 6 hours after discharge to the ward (n = 47).
Outcomes	Nausea (0 ‐ 24 h), vomiting (0 ‐ 24 h).
Notes	Reported separate incidence of intraoperative nausea and vomiting. Rescue antiemetic was ondansetron 4 mg IV during operations, or cyclizine 50 mg IM 8‐hourly after operations. Rescue antiemetic use reported as mean dose (no data for risk of rescue cyclizine use). Side effect of acupressure bands was "some localized discomfort in a small number of women". No details about funding source or any declarations of interest among authors.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Insufficient information.
Allocation concealment (selection bias)	Unclear risk	Insufficient information.
Blinding of patients (performance bias) All outcomes	Low risk	Authors took adequate steps to make interventions appear similar.
Blinding of healthcare providers (performance bias) All outcomes	Low risk	"Bands were not visible to the assessing anaesthetist during operations, as patients' arms were covered with surgical drapes".
Blinding of outcome assessor (detection bias) All outcomes	Low risk	"After 6 and 24h, an anaesthetist blinded to the therapy noted whether nausea, retching or vomiting had occurred".
Incomplete outcome data (attrition bias) All outcomes	Low risk	Reasons for withdrawals were given. No missing data reported for 94 participants analysed.
Selective reporting (reporting bias)	High risk	Risk of rescue cyclizine not reported separately for nausea and vomiting outcomes.
Other bias	Low risk	Baseline characteristics were comparable. "The groups were comparable with respect to age, weight, height and bupivacaine dose".