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. 2015 Nov 2;2015(11):CD003281. doi: 10.1002/14651858.CD003281.pub4

Ravi 2010.

Methods Parallel‐group randomized trial, conducted in India. Study dates not reported.
Participants 50 people aged 4 ‐ 60 years with ASA physical status I or II undergoing surgery (general, laparoscopic, ENT, paediatric, orthopaedic, obstetric, gynaecological) under general anaesthesia. Exclusion criteria: people with cardiovascular disease, central nervous system problems, previous history of PONV and motion sickness, and smokers.
Interventions Group 1: P6 acupoint injection with 50% 0.2 ml dextrose after induction of anaesthesia (n = 25).
Group 2: Ondansetron (50 µg/kg) at end of surgery (n = 25).
Outcomes Nausea (0 ‐6 h), vomiting (0 ‐6 h), rescue antiemetic (ondansetron 4 mg)
Notes Subgroup analysis for adults and children not done as overall population was mixed in age range (4 ‐ 60 years).
No details about funding source or any declarations of interest among authors.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer‐generated random numbers table.
Allocation concealment (selection bias) Unclear risk Insufficient details given.
Blinding of patients (performance bias) 
 All outcomes Low risk "Both patients and doctors were unaware of the group allocation."
Blinding of healthcare providers (performance bias) 
 All outcomes Low risk "Both patients and doctors were unaware of the group allocation."
Blinding of outcome assessor (detection bias) 
 All outcomes Low risk "An anaesthetist blinded for the study assessed the presence of nausea and vomiting."
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No missing data reported for the 50 participants analysed.
Selective reporting (reporting bias) High risk Incidence of rescue ondansetron 4 mg for intolerable PONV in recovery room and postoperative ward not reported.
Other bias Low risk Age, sex ratio, weight of participants and duration of surgery were similar between groups.