Samad 2003.

Methods	Parallel‐group randomized trial, conducted in Pakistan. Study dates not reported.
Participants	50 people (18 ‐ 60 y) undergoing laparoscopic cholecystectomy. Exclusion: obesity (weight > 80 kg), diabetics, people with history of PONV, people receiving antiemetics and histamine H₂ antagonists.
Interventions	Acupressure band on right hand at P6 acupoint ½ h before induction of anaesthesia, and kept on for 6 hours after surgery (n = 25). Sham acupressure band on right hand with plastic bead placed on the dorsum of forearm (n = 25).
Outcomes	Nausea (0 ‐ 6 h), vomiting (0 ‐ 6 h), risk of rescue antiemetic drug, side effects.
Notes	Rescue antiemetic was metoclopramide 10 mg IV for nausea or vomiting. No side effects or complications associated with either intervention. No details about funding source or any declarations of interest among authors.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"Patients were randomly assigned by random table number to either group..".
Allocation concealment (selection bias)	Unclear risk	Insufficient information.
Blinding of patients (performance bias) All outcomes	Low risk	Authors took adequate steps to make interventions appear similar.
Blinding of healthcare providers (performance bias) All outcomes	Unclear risk	Insufficient information.
Blinding of outcome assessor (detection bias) All outcomes	Low risk	"A blinded observer in the recovery room (one of the investigator not involved in applying acupressure band) evaluated the patients for presence of nausea and vomiting...".
Incomplete outcome data (attrition bias) All outcomes	Low risk	No missing data reported for 50 participants analysed.
Selective reporting (reporting bias)	Low risk	All expected outcomes reported.
Other bias	Low risk	Baseline characteristics were comparable. "There was no statistically significant difference with respect to age, sex, weight and duration of surgery between the two groups".