White 2002.

Methods	Parallel‐group randomized trial, conducted in United States. Study dates not reported.
Participants	120 adults undergoing elective plastic surgery. Excluded: antiemetic medication within 24 h before surgery, pregnancy, using permanent cardiac pacemaker, previous experience with acustimulation treatment, experiencing vomiting or retching within 24 h before surgery. No participants withdrew before discharge from hospital, 5 participants withdrew from study at 72 hours follow‐up.
Interventions	Group 1: ondansetron 4 mg and inactive acustimulation device (ReliefBand) at P6 acupoint on arrival in the recovery room. Device worn for 72 hours after surgery (n = 40). Group 2: saline 2 mL and active acustimulation device (ReliefBand) at P6 acupoint on arrival in the recovery room. Device worn for 72 hours after surgery (n = 40). Group 3: ondansetron 4 mg and active acu‐stimulation device (ReliefBand) at P6 acupoint on arrival in the recovery room. Device worn for 72 hours after surgery (n = 40).
Outcomes	Nausea (0 ‐ hospital discharge), vomiting (0 ‐ hospital discharge), risk of rescue antiemetic drug, side effects.
Notes	Rescue antiemetic was metoclopramide 10 mg IV if persistent nausea or vomiting, or retching lasting more than 10 min. No swelling at wrist or erythema reported. No outcome measures (0 ‐ 72 h) given in the paper. Funding source from department. First author received past funding from both Woodside Biomedical systems and GlaxoSmith‐Kline.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"Patients were randomly assigned to one of three treatment groups using a computer‐generated random number table...".
Allocation concealment (selection bias)	Unclear risk	Insufficient information.
Blinding of patients (performance bias) All outcomes	Low risk	All participants were told that the ReliefBand acu‐stimulation device produces a sensation which they may or may not feel to minimize bias. Participants recorded outcome measures in a participant diary.
Blinding of healthcare providers (performance bias) All outcomes	Unclear risk	Insufficient information.
Blinding of outcome assessor (detection bias) All outcomes	Low risk	All participants were told that the ReliefBand acustimulation device produces a sensation which they may or may not feel to minimize bias. Participants recorded outcome measures in a participant diary.
Incomplete outcome data (attrition bias) All outcomes	Low risk	1 participant lost to follow‐up in ondansetron group, 1 lost to follow‐up in acu‐stimulation group, and 3 lost to follow‐up in combination group. Author used intention to treat analysis.
Selective reporting (reporting bias)	Low risk	All expected outcomes were reported.
Other bias	Low risk	Baseline characteristics were comparable. "The three treatment groups were comparable with respect to demographic characteristics, pre‐existing risk factors for development of PONV, and preoperative nausea scores".