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. 2015 Nov 2;2015(11):CD003281. doi: 10.1002/14651858.CD003281.pub4

Yentis 1992.

Methods Parallel‐group randomized trial, conducted in Canada. Study dates not reported.
Participants 90 children (1 ‐ 16 y) undergoing strabismus surgery. 1e child in each of the 3 groups could not be contacted after surgery.
Interventions Group 1: acupuncture at P6 acupoint on right wrist with 5 min of manual stimulation after induction of anaesthesia (n = 30).
Group 2: antiemetic group had 0.075 mg/kg droperidol IV after induction of anaesthesia (n = 30).
Group 3: acupuncture (as in Group 1) and droperidol (as in Group 2) treatment (n = 30).
Outcomes Vomiting (0 ‐ 48 h), risk of rescue antiemetic drug, side effects of treatment.
Notes Rescue antiemetic was dimenhydrinate IM. Restlessness more frequent in droperidol group than acupuncture group. Risk of vomiting before discharge from hospital also reported in paper.
No details about funding source or any declarations of interest among authors.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information.
Allocation concealment (selection bias) Unclear risk Insufficient information.
Blinding of patients (performance bias) 
 All outcomes Low risk "Whether or not patients received droperidol, both treatments or acupuncture alone, was unknown to the staff, the patients and their parents".
Blinding of healthcare providers (performance bias) 
 All outcomes Low risk "Whether or not patients received droperidol, both treatments or acupuncture alone, was unknown to the staff, the patients and their parents".
Blinding of outcome assessor (detection bias) 
 All outcomes Unclear risk Insufficient information.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk One participant in each group lost to follow‐up.
 Comment: unlikely to bias summary estimate.
Selective reporting (reporting bias) High risk Need for rescue antiemetic not reported in Results.
Nausea was not reported because it may have been difficult to assess in younger children.
Other bias Low risk Baseline characteristics were comparable. "Age, weight, number of muscles repaired and duration of anaesthesia did not differ among the groups".