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. 2015 Nov 2;2015(11):CD003281. doi: 10.1002/14651858.CD003281.pub4

Zhu 2010.

Methods Parallel‐group randomized trial, conducted in China. Study dates not reported.
Participants 120 women undergoing gynaecological laparoscopic surgery, ASA I ‐ II, for general anaesthesia.
Interventions Group 1: dilute droperidol injected into bilateral P6 acupoints using an acupuncture needle at 20 min before surgery. Twisted needle at depth of 2.5 cm to 3 cm to get needling sensation, and retained for 10 min (n = 40).
Group 2: 2.5 mg droperidol IV 20 minutes before surgery (n = 40).
Group 3: no treatment.
Outcomes Nausea (0 ‐ 24 h), vomiting (0 ‐ 24 h), side effects of droperidol.
Notes No treatment data were excluded from analysis. No drowsiness, anxiety or extrapyramidal reactions observed in any groups.
No details about any declarations of interest among authors.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Participants were randomized into 3 groups using a random‐numbers table.
Allocation concealment (selection bias) Unclear risk Sequential but no other details given.
Blinding of patients (performance bias) 
 All outcomes High risk Participants unlikely to be blinded as they were conscious in order to feel needling sensation of acupuncture.
Blinding of healthcare providers (performance bias) 
 All outcomes High risk No attempt to mask sham acupuncture in droperidol group.
Blinding of outcome assessor (detection bias) 
 All outcomes Unclear risk Insufficient details given.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No missing data recorded for 120 participants analysed.
Selective reporting (reporting bias) Low risk All expected outcomes reported.
Other bias Low risk Age and type of surgery among groups were comparable.