Zhu 2010.
Methods | Parallel‐group randomized trial, conducted in China. Study dates not reported. | |
Participants | 120 women undergoing gynaecological laparoscopic surgery, ASA I ‐ II, for general anaesthesia. | |
Interventions | Group 1: dilute droperidol injected into bilateral P6 acupoints using an acupuncture needle at 20 min before surgery. Twisted needle at depth of 2.5 cm to 3 cm to get needling sensation, and retained for 10 min (n = 40). Group 2: 2.5 mg droperidol IV 20 minutes before surgery (n = 40). Group 3: no treatment. |
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Outcomes | Nausea (0 ‐ 24 h), vomiting (0 ‐ 24 h), side effects of droperidol. | |
Notes | No treatment data were excluded from analysis. No drowsiness, anxiety or extrapyramidal reactions observed in any groups. No details about any declarations of interest among authors. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Participants were randomized into 3 groups using a random‐numbers table. |
Allocation concealment (selection bias) | Unclear risk | Sequential but no other details given. |
Blinding of patients (performance bias) All outcomes | High risk | Participants unlikely to be blinded as they were conscious in order to feel needling sensation of acupuncture. |
Blinding of healthcare providers (performance bias) All outcomes | High risk | No attempt to mask sham acupuncture in droperidol group. |
Blinding of outcome assessor (detection bias) All outcomes | Unclear risk | Insufficient details given. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No missing data recorded for 120 participants analysed. |
Selective reporting (reporting bias) | Low risk | All expected outcomes reported. |
Other bias | Low risk | Age and type of surgery among groups were comparable. |