Lv 2013.
Trial name or title | PC6 acupoint stimulation for prevention of postoperative nausea and vomiting in patients undergoing craniotomy |
Methods | Single‐centred, double‐blinded, 5‐arm, parallel‐group RCT |
Participants | People undergoing craniotomy |
Interventions | Group 1: Ondansetron 8 mg IV before skin closure and PC6 acupuncture bilaterally for 30 min after regaining consciousness from general anaesthesia with stimulation every 10 min to keep de qi sensation. Group 2: Ondansetron 8 mg IV before skin closure and sham PC6 acupuncture bilaterally for 30 min after regaining consciousness from general anaesthesia with no stimulation. Group 3: Ondansetron 8 mg IV before skin closure and PC6 stimulation via active TENS electrodes bilaterally for 30 min after regaining consciousness from general anaesthesia with stimulation intensity and frequency set to when de qi sensation is felt. Group 4: Ondansetron 8 mg IV before skin closure and PC6 stimulation via inactive TENS electrodes bilaterally for 30 min after regaining consciousness from general anaesthesia with no stimulation intensity and frequency. Group 5: Ondansetron 8 mg IV before skin closure. |
Outcomes | Nausea (0 ‐ 24 h), vomiting (0 ‐ 24 h), rescue antiemetic (metoclopramide) |
Starting date | January 2013 |
Contact information | zhenjiuhuaxi@163.com. |
Notes | Protocol published in Trials 2013 May 28;14:153. doi: 10.1186/1745‐6215‐14‐153. This study is registered with the Chinese Clinical Trial Registry: ChiCTR‐TRC‐13003026. |
h = hours ICU = Intensive care unit IV = intravenous PC6 = pericardium acupoint RCT = randomized controlled trial TENS = transcutaneous electrical nerve stimulation