Table 2.
Multiple logistic regression analysis of the association of clinicopathologic characteristics with axillary lymph node metastases in patients with breast cancer.
| Characteristics | HR | CI | p-value |
|---|---|---|---|
| Model 1 | |||
| Tumor location | |||
| Inner quadrant vs. outer quadrant | 0.635 | 0.450-0.896 | 0.010 |
| Central vs. outer quadrant | 0.825 | 0.535-1.272 | 0.383 |
| Tumor stage | |||
| pT2 vs. pT1 | 1.290 | 0.961-1.732 | 0.090 |
| pT3 vs. pT1 | 2.586 | 1.405-4.762 | 0.002 |
| pT4 vs. pT1 | 3.779 | 1.834-7.788 | < 0.001 |
| Grade | |||
| II vs. I | 2.266 | 1.258-4.085 | 0.006 |
| III vs. I | 3.456 | 1.925-6.206 | < 0.001 |
| Lymphovascular invasion | |||
| Positive vs. negative | 9.434 | 4.430-20.093 | < 0.001 |
| Breast cancer subtype | |||
| HR+/HER2- vs. HR-/HER2- | 1.258 | 0.819-1.931 | 0.294 |
| HR+/HER2+ vs. HR-/HER2- | 1.869 | 1.133-3.084 | 0.014 |
| HR-/HER2+ vs. HR-/HER2- | 1.640 | 0.986-2.729 | 0.057 |
| Model 2 | |||
| Tumor location | |||
| Inner quadrant vs. outer quadrant | 0.626 | 0.443-0.885 | 0.008 |
| Central vs. outer quadrant | 0.818 | 0.529-1.265 | 0.366 |
| Tumor stage | |||
| pT2 vs. pT1 | 1.321 | 0.984-1.775 | 0.064 |
| pT3 vs. pT1 | 2.530 | 1.365-4.691 | 0.003 |
| pT4 vs. pT1 | 3.143 | 1.494-6.612 | 0.003 |
| Grade | |||
| II vs. I | 2.192 | 1.225-3.922 | 0.008 |
| III vs. I | 3.482 | 1.949-6.220 | < 0.001 |
| Lymphovascular invasion | |||
| Positive vs. negative | 10.061 | 4.679-21.632 | < 0.001 |
| CEA | |||
| High vs. normal | 2.139 | 1.261-3.630 | 0.005 |
| CA15-3 | |||
| High vs. normal | 2.012 | 1.321-3.064 | 0.001 |
| Breast cancer subtype | |||
| HR+/HER2- vs. HR-/HER2- | 1.283 | 0.832-1.979 | 0.259 |
| HR+/HER2+ vs. HR-/HER2- | 1.790 | 1.077-2.974 | 0.025 |
| HR-/HER2+ vs. HR-/HER2- | 1.522 | 0.904-2.563 | 0.114 |