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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Cell Signal. 2015 Oct 28;28(1):91–99. doi: 10.1016/j.cellsig.2015.10.018

Figure 3. PLCβ2-TRAX interactions in MDA MB231 cells are affected by γ-synuclein knockdown.

Figure 3

A- Normalized change in fluorescence intensity of 2 nM CPM- PLCβ2 in solution as purified TRAX is added in the presence or absence of 100nM γ-synuclein. B- Co-immunofluorescence studies showing the colocalization of PLCβ2 (green) and TRAX (red) in MDA MB 231 cells treated with control (n=41) or γ-synuclein (n=75) siRNA. Pearson’s coefficient between the two groups is statistically significant (p<0.001, Student’s t-test. Positive control= 0.65 +/− 0.12, negative control= 0.03 +/− 0.08).