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. Author manuscript; available in PMC: 2017 Jan 15.
Published in final edited form as: Behav Brain Res. 2015 Oct 14;297:196–203. doi: 10.1016/j.bbr.2015.10.013

Figure 1.

Figure 1

Ethanol drinking in WT and Sig-1R KO mice (n=9–10/genotype). (A, B) Mice were given access to escalating concentrations of ethanol (3%, 6% and 20% v/v) in a home cage, two bottle choice paradigm. (C, D) Mice were given access for 14 consecutive days to a 10% v/v ethanol solution in a two bottle choice paradigm. Data represent Mean ± SEM. $ p≤0.1, * p≤0.05, ** p≤0.01, *** p≤0.001 vs. WT mice (Student’s t test).