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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Ann Thorac Surg. 2015 Aug 13;100(6):2048–2053. doi: 10.1016/j.athoracsur.2015.05.100

Table 3.

Cox proportional hazards model identifying factors associated with long-term mortality in patients with clinical stage I NSCLC

Patient and Treatment Variables Hazard ratio (HR) with 95% Confidence Interval (CI) p-Value
Age 1.03 (1.03–1.03) <0.001
Male gender 1.37 (1.33–1.42) <0.001
Caucasian Race 1.08 (1.02–1.15) 0.007
Academic Facility 0.96 (0.93–0.99) 0.03
Urban Location 0.96 (0.92–0.99) 0.02
Income >$35,000 0.90 (0.87–0.93) <0.001
Charlson Score =1 1.14 (1.10–1.18) <0.001
Charlson Score =2 1.49 (1.42–1.56) <0.001
Tumor Size (mm) 1.03 (1.02–1.03) <0.001
Clinical T2 Status 1.24 (1.19–1.28) <0.001
Positive Tumor Margin 1.49 (1.39–1.60) <0.001
Upstaged Tumor 1.85 (1.78–1.92) <0.001
Number of Lymph Nodes Examined (n) – all patients
n=0 1.00 n/a
n=1–3 0.80 (0.74–0.86) <0.001
n=4–6 0.69 (0.65–0.75) <0.001
n=7–9 0.67 (0.62–0.72) <0.001
n=10–12 0.64 (0.59–0.69) <0.001
n=13–15 0.65 (0.60–0.71) <0.001
n=16–18 0.62 (0.56–0.69) <0.001
n>18 0.66 (0.61–0.72) <0.001
Number of Lymph Nodes Examined – Non-upstaged only
n=0 1.00 n/a
n=1–3 0.78 (0.72–0.84) <0.001
n=4–6 0.69 (0.64–0.74) <0.001
n=7–9 0.65 (0.60–0.71) <0.001
n=10–12 0.64 (0.58–0.69) <0.001
n=13–15 0.66 (0.60–0.73) <0.001
n=16–18 0.64 (0.57–0.72) <0.001
n>18 0.67 (0.61–0.74) <0.001