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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Nutr Biochem. 2015 Aug 13;26(12):1479–1490. doi: 10.1016/j.jnutbio.2015.07.022

Figure 3.

Figure 3

Immunohistochemical analysis of cerebrovascular Aβ deposition in the hippocampus of CNTRL (control), EVOO-3m and EVOO-6m TgSwDI mice. Representative hippocampus sections from all treatment groups were double-immunostained with 6E10 for detection of Aβ (Green) and collagen-VI to identify brain microvessels (Red). Quantification of cerebrovascular Aβ deposition (CAA pathogenesis) as a % of Aβ-immunoreactive vessels demonstrated a significant reduction in microvascular Aβ deposits only in the hippocampus of EVOO-6m group. Data is presented as mean±SEM of 4–6 mice in each group. Scale bar, 50 µm (ns, not significant; ** P<0.01).