Skip to main content
. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Autoimmun. 2015 Aug 28;65:82–89. doi: 10.1016/j.jaut.2015.08.010

Figure 5. NF-κB signaling pathway in the differentiation of osteoclast from MDSCs.

Figure 5

MDSCs from the bone marrow of mice with CIA or normal mice were cultured in the presence of 50ng/ml M-CSF and 100ng/ml RANKL with or without Bay 11-7082 or IκB kinase inhibitor peptide for 12 days. (A) Cells were stained for TRAP or with FITC-phalloidin. Representative images are presented. (B) TRAP+ osteoclasts in each well were quantified and are shown as mean ± SD. The results represent three independent experiments. **p<0.01