Fig. 12.
Simulation of the parasitemia levels of a malaria infection starting at day 5 with 1 merozoite per 10 million RBCs and terminated by chemical intervention at day 20. Panel A shows the levels of infected RBCs (iRBCs) and panel B the levels of free merozoites. Parasites are assumed to spend one time point (1hr) in their free stage, as merozoites, after which all of them infect RBCs. At the end of their intraerythrotic life cycle, of 48 hours, 16 new merozoites are released from each iRBC. The drug is assumed to kill 4/5 of all iRBCs per hour.