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Guggulsterone induces apoptosis in human HepG2 and L-02 cells. Human HepG2 (A) and L-02 cells (B) were treated with 0 μmol/L, 50 μmol/L and 75 μmol/L of GS for 24 h and cell apoptosis was investigated using annexin V-FITC and PI. GS significantly increased HepG2 cell apoptosis in a dose-dependent manner. bP < 0.01, vs the control group.
