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. 2015 Dec 15;10(12):e0144703. doi: 10.1371/journal.pone.0144703

Fig 12. Schematic diagram depicting the distribution of major pH regulators in maturation-stage ameloblasts.

Fig 12

Cftr, Slc26a1, Slc26a4, Slc26a6 and Slc26a7 are localized to the apical membrane and Slc26a1, Slc26a6 and Slc26a7 physically interact with Cftr to form regulation complexes. Slc26a7 is also found on the endo-lysosomal membrane. Ae2, Nhe1 and NBCe1 are localized basolaterally. Clcn7 is expressed on the endo-lysosomal membrane. CA2 exhibits intracellular distribution whereas CA6 functions in extracellular enamel matrix. Lamp1 in this image was used as a marker of late lysosomes.