Table 1.
Top 20 genes downregulated or upregulated by SCVS compared with same sex controls for females and males
| Gene name | Fold change | p value | Gene name | Fold change | p value |
|---|---|---|---|---|---|
| Female down | Male down | ||||
| Eif4e3 | −2.577990489 | 0.005651417 | Gm14398 | −3.383830645 | 0.005096422 |
| Pax9 | −2.434715154 | 0.006331814 | BC107364 | −2.915796547 | 0.002979085 |
| Gm13833 | −2.403345361 | 0.004448435 | Cdh3 | −2.913895317 | 0.028056667 |
| C030005K15Rik | −2.215372988 | 0.025409394 | snoU105B | −2.885983623 | 0.001437604 |
| Gm9043 | −2.180304737 | 0.034446421 | CT030723.1 | −2.678330083 | 0.005915608 |
| Pawr | −2.144101779 | 0.016350813 | En1 | −2.677377799 | 0.014496827 |
| 4930404N11Rik | −2.134035973 | 0.007781197 | Gm10566 | −2.632350505 | 0.004650241 |
| Gm5546 | −2.103048946 | 0.007694025 | Gm16675 | −2.632350505 | 0.009281196 |
| Gm13634 | −2.099684564 | 0.010428945 | Rab44 | −2.628757266 | 0.04532264 |
| AC140327.1 | −2.08862837 | 0.029437298 | Gm572 | −2.545880965 | 0.013394635 |
| 1700020C07Rik | −2.080896077 | 0.015118536 | Apon | −2.504881626 | 0.017774897 |
| Gm16161 | −2.049360086 | 0.027645093 | Ptprq | −2.472708755 | 0.016148697 |
| Gm11942 | −2.016659894 | 0.007862275 | Glt28d2 | −2.465520661 | 0.017331428 |
| Slfn3 | −2.016567555 | 0.026341926 | Igfn1 | −2.425890994 | 0.021956617 |
| Hmgn2-ps1 | −2.014701945 | 0.044670803 | Gm12532 | −2.424408816 | 0.009856372 |
| Npb | −1.974874424 | 0.036187813 | Aplnr | −2.403880885 | 0.035825609 |
| Gm14225 | −1.942222579 | 0.038747955 | Il17b | −2.402915763 | 0.008693424 |
| AC026231.1 | −1.893124397 | 0.025550695 | Clcnka | −2.398613973 | 0.017167249 |
| Frzb | −1.87411723 | 0.018244063 | Pkp3 | −2.392942641 | 0.012595497 |
| 4933426D04Rik | −1.873191358 | 0.002186083 | Wdr86 | −2.376940462 | 0.024303922 |
| Female up | Male up | ||||
| Nccrp1 | 2.445511901 | 0.015416852 | Gm8399 | 3.50912188 | 0.001241839 |
| Gm15178 | 2.333921875 | 0.009174014 | Gm13189 | 3.439868478 | 0.002654011 |
| Fam159b | 2.307178789 | 0.005304213 | Gm3636 | 2.947915088 | 0.001976213 |
| Ghsr | 2.214274204 | 0.046910918 | Gm5915 | 2.695650565 | 0.010436352 |
| Lctl | 2.206042282 | 0.003435926 | Fam183b | 2.613476106 | 0.000443822 |
| 5830403M04Rik | 2.196357819 | 0.01632869 | Snord107 | 2.504122381 | 0.006862771 |
| Morn3 | 2.195286458 | 0.016634419 | Gm17645 | 2.424392771 | 0.015338314 |
| Gm12841 | 2.178963909 | 0.023103044 | Oas1a | 2.403928046 | 0.005717344 |
| Muc4 | 2.156227971 | 0.046397596 | Gm8281 | 2.39576758 | 0.009321205 |
| AC153147.1 | 2.065958759 | 0.039141575 | Tmem212 | 2.374337295 | 0.009727819 |
| Gm12970 | 2.059553572 | 0.011745348 | Gm6030 | 2.281421602 | 0.009890373 |
| Slc22a7 | 2.050508464 | 0.015854286 | Gm14027 | 2.266149588 | 0.016576487 |
| Lsm3 | 2.036374973 | 0.012540967 | Ifitm6 | 2.237713216 | 0.028811406 |
| Trp53tg5 | 2.015448642 | 0.022799387 | Gm17210 | 2.201291602 | 0.007395269 |
| Gm14027 | 2.000153184 | 0.032909893 | Gm11160 | 2.184258988 | 0.010804558 |
| Ccl11 | 1.999290666 | 0.03748544 | 7SK | 2.138252467 | 0.015927376 |
| Hist1h4i | 1.995495403 | 0.032921574 | 9030025P20Rik | 2.120186917 | 0.024628307 |
| Fam115c | 1.984655117 | 0.004331027 | 4932411N23Rik | 2.078502283 | 0.027761728 |
| Uncx | 1.955945635 | 0.025358013 | Calca | 2.052551148 | 0.028201798 |
| RP24-372P19.10.1 | 1.951580501 | 0.024900192 | Gm11418 | 2.022765318 | 0.032107609 |