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CLH-1 is a pH-sensitive inwardly rectifying anion channel. A, B, Example traces of current from a CLH-1 (A) and a noninjected (B) oocyte at an extracellular pH of 7.2, clamped at voltages ranging from −160 mV to 100 mV. C, The averaged current–voltage relationships of CLH-1 (dark circles, n = 10) and noninjected (open triangles, n = 9) oocytes at pH 7.2. D–F, Same as in A–C for pH 4.2 (CLH-1, n = 11; noninjected, n = 6).
