Table 1.

Summary of the findings of glial cell reductions within the brain of depressed.

Cortical region	Glial density	Neuronal size	Reference
DLPFC	Decrease in glia	20%	Cotter et al. (2002)
Supra and infragranular layers of	Dec. glia	5–7%	Rajkowska et al. (1999)
DLPFC and OrbitoFrontal Cortex (OFC)
Subgenual Anterior Cingulate changes in neuronal size/shape	Dec. in Glia (Area 24) across all layers	Selective decrease in layer Vb and	Gittins and Harrison (2011)
Anterior cingulate cortex	Dec. in Glia density layer 6 (22%)	23% layer 6	Cotter et al. (2001)
Hippocampus (CA1 region)	Dec. in astrocytes	Not reported	Gos et al. (2013)
Amygdala	Dec. in glia and oligodendrocytes	Not reported	Bowley et al. (2002) and Hamidi et al. (2004)