Table 2.

Summary of the therapeutic drugs that target glial cells.

Neuropsychiatric disorder	Glial cells affected	Therapeutics targeting glial cells	Glial cells responsive to therapeutics
Major depressive disorder	Astrocytes	Riluzole (Yoshizumi et al., 2012)	-Astrocytes
	Microglia	Fluoxetine, Paroxetine (Allaman et al., 2011)	-Oligodendrocyte
	Oligodendrocytes	Ceftriaxone (Li et al., 2012)	progenitors
		Minocycline (Hinwood et al., 2012)	-Microglia
Bipolar disorder	Oligodendrocytes	Lithium (Orre et al., 2009; Souza Ade et al., 2010)	-Astrocytes
	Astrocytes		-Oligodendrocyte
	Microglia		progenitors
Anxiety disorders	Oligodendrocytes	Riluzole (Pittenger et al., 2008)	-Astrocytes
	Astrocytes	Benzodiazepines (Patte et al., 1999)
Schizophrenia	Astrocytes	Minocycline (Chaudhry et al., 2012)	-Microglia
	Microglia	Risperidone (Kato et al., 2007)
	Oligodendrocytes	Chlorpromazine and loxapine (Labuzek et al., 2005)
Substance use disorders	Astrocytes	Ibudilast, AV1013, minocycline (Snider et al., 2013)	-Microglia
	Microglia
	Oligodendrocytes
Alexander disease	Astrocytes