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. 2015 Dec 16;9:148. doi: 10.3389/fncom.2015.00148

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Copyright © 2015 Zippo, Castiglioni, Borsa and Biella.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Network statistics in the follow-up analysis of rs-fMRI volumes. The Mann-Kendal monotonic trend test shows that only CF is able to distinguish the two times of investigation (initial screening and after 2 years) in all three pathological classes (EMCI, LMCI, AD). For detailed significance see the Results section. C, indicates the clustering coefficient; L, the characteristic path length; Q, the modularity; Ω, the average node strength; BC, the betweenness centrality; EBC, the edge betweenness centrality; CF, the proposed measure called Compression Flow; and #Nodes represents the number of nodes.