Table 4.

Treatment goals for medical regulation

Medication	Treatment goals	Intensification of treatment during standardisation	Intensification of treatment at follow-ups
Antidiabetics	HbA1c ≤48 mol/mol	HbA1c >64 mmol/L or 5 mmol/mol increment	HbA1c >58 mmol/L or 5 mmol/mol increment
Antihypertensive	BP ≤130/80 mm Hg	BP >150/95 mm Hg	BP >140/85 mm Hg
Antilipids	LDL ≤2.0 mmol/L TG ≤5.0 mmol/L	LDL >2.0 mmol/L TG >5.0 mmol/L	LDL >2.0 mmol/L TG >5.0 mmol/L

The table shows treatment goals for the U-TURN intervention and intensification of treatment. If the treatment target is reached, the dose of the compound is halved at the following control time point (3 months later). In case of unchanged values or an additional drop, the compound is then discontinued.

BP, blood pressure; HbA1c, glycated haemoglobin; LDL, low-density lipoproteins; TG, triglycerides.