. 2015 Dec 11;5(12):e007291. doi: 10.1136/bmjopen-2014-007291

Table 4.

Herbal medicines in the included studies

References	Formula	Composition of formula
Hu 2012³⁵	ZWD	Processed aconite (Fu Zi, Radix Lateralis Praeparata Aconiti Carmichaeli) 20 g, Poria (Fu Ling, Scierotium Poriae Cocos) 15 g, White Atractylodes Rhizome (Bai Zhu, Rhizoma Atractylodis Macrocephalae) 10 g, White Peony Root (Bai Shao, Radix Albus Paeoniae Lactiflorae) 25 g, and fresh ginger (Sheng Jiang, Rhizoma Zingiberis Recens) 8 g
Li and Shen 2012³⁶	ZWD	Processed aconite (Fu Zi, Radix Lateralis Praeparata Aconiti Carmichaeli) 15 g, Poria (Fu Ling, Scierotium Poriae Cocos) 20 g, White Atractylodes Rhizome (Bai Zhu, Rhizoma Atractylodis Macrocephalae) 15 g, White Peony Root (Bai Shao, Radix Albus Paeoniae Lactiflorae) 20 g, and fresh ginger (Sheng Jiang, Rhizoma Zingiberis Recens) 9 g
Shen 2004³⁷	Modified ZWD	Processed aconite (Fu Zi, Radix Lateralis Praeparata Aconiti Carmichaeli) 3–6 g, Poria (Fu Ling, Scierotium Poriae Cocos) 10–18 g, White Atractylodes Rhizome (Bai Zhu, Rhizoma Atractylodis Macrocephalae) 10 g, White Peony Root (Bai Shao, Radix Albus Paeoniae Lactiflorae) 10 g, fresh ginger (Sheng Jiang, Rhizoma Zingiberis Recens) 10 g, Alisma (Ze Xie, Rhizoma Alismatis) 10 g, Baical Skullcap Root (Huang Qin, Radix Scutellariae Baicalensis) 10–30 g, and Achyranthes Root (Niu Xi, Achyranthis Bidentatae Radix) 10 g. If aversion to cold and deadlimb were found, Aerial Parts of Epimedium (Yin Yang Huo, Herba Epimedii) and Chinese Taxillus Twig (Sang Ji Sheng, Herba Taxilli) were added. If tinnitus was found, Magnetite (Cishi, Magnetitum) and Gambir Vine Stems and Thorns (Gou Teng, Ramulus Uncariae Cum Uncis) were added. If palpitation was found, Liquorice Root (Gan Cao, Radix Glycyrrhizae) and Ophiopogon (Mai Dong, Tuber Ophiopogonis Japonici) were added. If cyanosis was found, Salvia Root (Dan Shen, Radix Salviae Miltiorrhizae) and Chinese Motherwort (Yi Mu Cao, Herba Leonuri Heterophylli) were added
Jiang et al 2013³⁸	Modified ZWD	Processed aconite (Fu Zi, Radix Lateralis Praeparatus Aconiti Carmichaeli) 30 g, Poria (Fu Ling, Scierotium Poriae Cocos) 30 g, White Atractylodes Rhizome (Bai Zhu, Rhizoma Atractylodis Macrocephalae) 30 g, White Peony Root (Bai Shao, Radix Albus Paeoniae Lactiflorae) 12 g, fresh ginger (Sheng Jiang, Rhizoma Zingiberis Recens) 20 g, Astragalus (Huang Qi, Radix Astragali Membranacei) 40 g, Hirsute Shiny Bugleweed Herb (Ze Lan, Herba Lycopi) 15 g, Salvia Root (Dan Shen, Radix Salviae Miltiorrhizae) 15 g, and Achyranthes Root (Niu Xi, Achyranthis Bidentatae Radix) 15 g. If significant oedema was found, Polyporus Sclerotium (Zhu Ling, Sclerotium Polypori Umbellati) 20 g, Cassia twig (Gui Zhi, Ramulus Cinnamomi Cassiae) 10 g, and Betel Husk (Da Fu Pi, Pericarpium Arecae Catechu) 20 g were added. If lassitude, aversion to cold, and soreness of waist and knee were found, Cuscuta Seed (Tu Si Zi, Cuscutae Semen) 20 g and Aerial Parts of Epimedium (Yin Yang Huo, Herba Epimedii) 20 g were added
Li 2009³⁹	Modified ZWD	Processed aconite (Fu Zi, Radix Lateralis Praeparatus Aconiti Carmichaeli) 6 g, Poria (Fu Ling, Scierotium Poriae Cocos) 12 g, White Atractylodes Rhizome (Bai Zhu, Rhizoma Atractylodis Macrocephalae) 9 g, White Peony Root (Bai Shao, Radix Albus Paeoniae Lactiflorae) 6 g, fresh ginger (Sheng Jiang, Rhizoma Zingiberis Recens) 3 tablets, Astragalus (Huang Qi, Radix Astragali Membranacei) 30 g, Earthworm (Di Long, Lumbricus) 9 g, Eucommia Bark (Du Zhong, Cortex Eucommiae Ulmoidis) 12 g, Chinese Taxillus Twig (Sang Ji Sheng, Herba Taxilli) 9 g, Achyranthes Root (Niu Xi, Achyranthis Bidentatae Radix) 9 g, and Notoginseng Root (San Qi, Radix Notoginseng) 6 g. If chest tightness was found, Bulb of Chinese Chive (Xie Bai, Bulbus Allii) was added. If palpitation was found, Spiny Jujube Kernel (Suan Zao Ren, Ziziphi Spinosi Semen) was added. If deadlimb was found, Gastrodia (Tian Ma, Gastrodiae Rhizoma) was added
Jiang 2009⁴⁰	Modified ZWD	Processed aconite (Fu Zi, Radix Lateralis Praeparatus Aconiti Carmichaeli) 15 g, Poria (Fu Ling, Scierotium Poriae Cocos) 15 g, White Atractylodes Rhizome (Bai Zhu, Rhizoma Atractylodis Macrocephalae) 15 g, White Peony Root (Bai Shao, Radix Albus Paeoniae Lactiflorae) 10 g, fresh ginger (Sheng Jiang, Rhizoma Zingiberis Recens) 10 g, Cassia twig (Gui Zhi, Ramulus Cinnamomi Cassiae) 12 g, and Liquorice Root (Gan Cao, Radix Glycyrrhizae) 10 g. If insomnia was found, Spiny Jujube Kernel (Suan Zao Ren, Ziziphi Spinosi Semen) 10 g and Arbor Vitae Seed (Bai Zi Ren, Semen Platycladi) 10 g were added. If digestive system symptoms were found, Codonopsis Root (Dang Shen, Radix Codonopsis Pilosulae) 30 g, Astragalus (Huang Qi, Radix Astragali Membranacei) 20 g, Tangerine Peel (Chen Pi, Pericarpium Citri Reticulatae) 10 g, and Amomum Fruit (Sha Ren, Amomi Semen seu Fructus) 6 g were added. If headache and dizziness were found, Astragalus (Huang Qi, Radix Astragali Membranacei) 20 g, Clears Heat and Expels Wind (Bai Zhi, Radix Angelicae Dahuricae) 10 g, and Szechuan Lovage Root (Chuan Xiong, Rhizoma Ligustici Chuanxiong) 10 g were added
Zhong 2014⁴¹	Modified ZWD	Processed aconite (Fu Zi, Radix Lateralis Praeparatus Aconiti Carmichaeli) 12 g, Poria (Fu Ling, Scierotium Poriae Cocos) 15 g, White Atractylodes Rhizome (Bai Zhu, Rhizoma Atractylodis Macrocephalae) 15 g, White Peony Root (Bai Shao, Radix Albus Paeoniae Lactiflorae) 15 g, fresh ginger (Sheng Jiang, Rhizoma Zingiberis Recens) 6 g, Oyster Shell (Mu Li, Concha Ostreae) 30 g, and Plantain Seed (Che Qian Zi, Semen Plantaginis) 9 g. If palpitation was found, Cassia twig (Gui Zhi, Ramulus Cinnamomi Cassiae) 10 g was added. If insomnia was found, Spiny Jujube Kernel (Suan Zao Ren, Ziziphi Spinosi Semen) 30 g and Fossilized Mammal Bones (Long Gu, Os Draconis) 30 g were added. If tinnitus was found, Magnetite (Ci Shi, Magnetitum) 30 g was added

ZWD, Zhen Wu Decoction.