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. 2015 Dec 16;9:468. doi: 10.3389/fnins.2015.00468

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Copyright © 2015 Morrison, Bamkole and Nicola.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Reward devaluation increases the proportion of trials in which subjects respond to the CS with a lever press. (A,B) Mean lever deflection count (A) and receptacle entry count (B) during the CS-on periods for the paired group (left) and unpaired group (right) in the last 4 days of training (blue) and in the test session (red). (C) Mean first response index for the paired group (left) and unpaired group (right) during the last 4 days of training (blue) and the test session (red). See Materials and Methods for details of index calculation. (D) Mean change in first response index from training to test session for the paired group (green) and the unpaired group (gray). All panels: error bars, ±SEM; asterisk, corrected p < 0.05; dagger, corrected or uncorrected p < 0.1. All unlabeled comparisons are non-significant (uncorrected p > 0.1).