Table 3.

Bivariate HR and multivariable adjusted HRs (AHR) for treatment failure or death among patients enrolled in treatment

	HR	95% CI	p Value	AHR	95% CI	p Value
Age	1.02	1.00 to 1.03	0.078	1.01	0.99 to 1.03	0.316
Female sex	1.07	0.72 to 1.61	0.730	1.03	0.60 to 1.76	0.918
Previous TB treatments	0.96	0.79 to 1.18	0.713
HIV	1.80	1.17 to 2.77	0.008	2.60	1.48 to 4.56	<0.001
Extrapulmonary disease	0.83	0.36 to 1.89	0.652
Cavitary disease	1.39	0.82 to 2.37	0.219
BMI (kg/m2)	0.90	0.82 to 0.98	0.016	0.88	0.81 to 0.96	0.006
Haemoglobin (g/dL)	0.93	0.86 to 1.00	0.043
Diabetes	1.25	0.57 to 2.72	0.579
Cor pulmonale	5.11	3.06 to 8.55	<0.001	3.61	1.56 to 8.32	0.003
Smoker	1.14	0.62 to 2.10	0.669
Drug use	1.32	0.63 to 2.73	0.463
Confirmed MDR	0.66	0.39 to 1.50	0.131	0.50	0.27 to 0.92	0.026
Resistant to HRES	1.18	0.66 to 2.11	0.578
CD4 count*	1.05	0.85 to 1.35	0.637

*Among HIV-infected patients; hazard radio reflects difference of 100 cells/mL³.

BMI, body mass index; HRES, isoniazid, rifampicin, ethambutol, streptomycin; MDR, multidrug resistant.