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Dabigatran dose levels and coagulation markers
| Dabigatran level (ng/mL) |
PT (NR: 11–15) |
APTT (NR: 25–35) |
||||
|---|---|---|---|---|---|---|
| Dose | Trough | Peak | Trough | Peak | Trough | Peak |
| 110 mg daily | <30 | Not done | 14 | 15 | 39 | 44 |
| 110 mg BD | <32 | 120 | 15 | Not done | 46 | Not done |
| 150 mg BD | <32 | 229 | 14 | 19 | 36 | 69 |
APTT, activated partial thromboplastin time; BD, twice daily; PT, prothrombin time; RE-LY, Randomized Evaluation of Long-Term Anti- coagulation Therapy; NR, normal range.
