Table 2.
Concentration of free fatty acid in different groups
| Group | C (FFAs) μmol/L | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Palmitic acid (c16:0) | Stearic acid (c18:0) | Oleic acid (c18:1) | Linoleic acid (c18:2) | Linolenic acid (c18:3) | Arachidonic acid (c20:4) | |
| Control | 298.73±10.01 | 179.63±6.65 | 322.5±19.84 | 514.23±14.52 | 29.12±2.56 | 91.23±6.54 |
| DOX | 364.98±12.45* | 239.01±9.14* | 385.2±17.89* | 555.62±19.54* | 59.6±3.89* | 118.94±8.79* |
| PPARα- | 412.01±15.96* | 264.53±8.78* | 411.2±19.24* | 599.87±18.74* | 77.08±4.52* | 132.25±5.96* |
| PPARα+ | 340.68±11.15* | 211.01±6.56* | 355.78±18.74* | 524.12±16.58* | 45.21±4.89* | 101.03±7.89* |
Free fatty acid was separated from cardiomyocytes and measured by HPLC method. Data are the mean ± SEM;
*
compared with control group, P<0.05.