Figure 1.

Histology, epithelial permeability, and serum CRP in colitis rats. Morphology of the rat colon after treatment with DSS for 0 (A), 4 (B), 6 (C), and 8 days (D). The histological score (E) and serum CRP (F) were also determined. The colonic epithelial barrier (G) was assessed by measuring the mucosal-to-blood permeation of FD4. Six rats were studied in each group. The results are presented as the means ± SEM. #P < 0.05 vs. control group; §P < 0.05 vs. the group of rats treated for four days; ¶P < 0.05 vs. the group of rats treated for six days. Original magnification, 200×.