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SASH1 inhibits thyroid cancer cell proliferation, migration and EMT through suppressing PI3K/Akt signaling pathway. (A) The levels of phosphorylated PI3K, total PI3K, phosphorylated Akt, total Akt, were detected in vector, pcDNA3.1-SASH1-transfected FTC133 cells by western blot analysis. Quantification of (B) p-PI3K/PI3K and (C) p-Akt/Akt. The results are expressed as mean ± SD and n=3 per group. *P<0.05 compared with the vector group.
