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Silencing of CCR7 affects MMPs activity expression by ELISA, and protein expression by western blot analysis. A. MMP-2 and MMP-9 levels were significantly decreased after silencing CCR7 as compared with the control cells. **P<0.05 vs. the control and ##P<0.01 vs. the VEGFC treated group. B. Protein expression levels of MMP-9 and MMP-2 were detected by western blot analysis after CCR7 silencing.
