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. 2015 Oct 1;8(10):12766–12774.

Figure 2.

Figure 2

Down-regulation of SEMA3F in CRC cells is associated with DNA methylation of SEMA3F gene promoter region. A: A schematic illustration of the CpG island of the SEMA3F gene, which spans from -965 to + 540 with respect to the transcription start site (+ 1): red vertical bars, the locations of the CpG sites. The regions of MSP were shown. B: DNA methylation of SEMA3F in FHC and CRC cell lines. SEMA3F was hypermethylated in SW620, and partially methylated in SW480 and HCT116, but not methylated in LoVo and FHC. C: MSP showing DNA methylation of SEMA3F in CRC tissue specimens and corresponding non-tumor tissues. M: methylated; U: unmethylated.