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. 2015 Oct 1;8(10):12820–12828.

Figure 4.

Figure 4

The mRNA and protein expression of SHH were measured by real-time PCR and western blotting respectively when MBMECs were treated with SHH-siRNA and SHH-transfected (A). Effect of SHH loss-of-function or gain-of-function on cell viability in MBMECs when treated with ox-LDL (100 mg/L) for 24 h (B). Effect of SHH loss-of-function or gain-of-function on cell apoptosis in MBMECs when treated with ox-LDL (100 mg/L) for 24 h (C). Effect of SHH loss-of-function or gain-of-function on caspase3 levels in MBMECs when treated with ox-LDL (100 mg/L) for 24 h (D). Effect of SHH loss-of-function or gain-of-function on caspase8 levels in MBMECs when treated with ox-LDL (100 mg/L) for 24 h (E). Values were expressed as mean ± SD, n = 3 in each group. *P < 0.05 versus control group.