Table 2.

Analysis of factors associated with lymph node metastasis

Clinicopathological factors	No	Lymph node metastasis (%)	P Value of univariate analysis	Multivariate analysis
				HR	95% CI	P Value
Gender			1.000
Male	104	8 (7.69)
Female	52	4 (7.69)
Age			0.352
< 60 years	121	8 (6.61)
≥ 60 years	35	4 (11.43)
Tumor size			< 0.001
0-10 mm	126	2 (1.59)
11-20 mm	19	2 (10.53)
> 20 mm	11	8 (72.73)
Invasion depth			< 0.001	3.295	1.508-7.200	0.003
T1	140	4 (2.86)
T2-4	16	8 (50.00)
Pathological grading			< 0.001
G1	137	4 (2.92)
G2	10	2 (20.00)
G3	9	6 (66.67)
Symptoms			0.997
Yes	102	12 (11.76)
No	54	0 (0)
Staging			0.991
I	140	0 (0)
II	4	0 (0)
III	12	12 (100)
1-cm stratification			< 0.001	13.124	2.068-71.073	0.006
≤ 1 cm	126	2 (1.59)
> 1 cm	30	10 (33.33)