Table 4.
Genotype distribution and allele frequency of four ABCA1 SNPs
| SNP | CHD (%) | Controls (%) | x2 | P |
|---|---|---|---|---|
| rs363717 (n = 1497) | ||||
| AA | 488 (66.2) | 448 (58.9) | 8.43 | 0.015 |
| AG | 219 (29.7) | 274 (36.1) | ||
| GG | 30 (4.1) | 38 (5.0) | ||
| G allele | 279 (18.9) | 350 (23.0) | 7.57 | 0.006 |
| rs4149339 (n = 1500) | ||||
| TT | 362 (48.9) | 372 (48.9) | 0.38 | 0.828 |
| CT | 332 (44.9) | 335 (44.1) | ||
| CC | 46 (6.2) | 53 (7.0) | ||
| C allele | 424 (28.6) | 441 (29.0) | 0.05 | 0.826 |
| rs4149338 (n = 1497) | ||||
| TT | 356 (48.3) | 363 (47.8) | 1.12 | 0.570 |
| CT | 335 (45.5) | 339 (44.6) | ||
| CC | 46 (6.2) | 58 (7.6) | ||
| C allele | 427 (29.0) | 455 (29.9) | 0.34 | 0.562 |
| rs2230808 (n = 1497) | ||||
| GG | 281 (38.1) | 310 (40.8) | 3.46 | 0.177 |
| AG | 378 (51.3) | 355 (46.7) | ||
| AA | 78 (10.6) | 95 (12.5) | ||
| A allele | 534 (36.2) | 545 (35.8) | 0.05 | 0.832 |
Data were analyzed by Pearson’s Chi-square test. Bold P values are statistically significant.