Figure 5.

Schematic representation of the Orpheus blood gas model. The model is made up of five compartments and two pumps. In two of these compartments (Artificial Lung, Native Lung), gas exchange occurs. Two compartments (Arterial Pool, Venous Pool) largely behave as passive conduits. In the final compartment (Tissue Pool), most metabolic activity occurs. The artificial lung is assumed to be perfused at a rate equal to that of the main arterial pump. The native lung is assumed to be perfused at a rate equal to the patient’s current cardiac output.