Table 3.
Hourly rate of bleeding (ICU).
| Group | 1-Hour Bleeding Rate (mL/kg/h) | 2-Hour Bleeding Rate (mL/kg/h) | 3-Hour Bleeding Rate (mL/kg/h) | 4-Hour Bleeding Rate (mL/kg/h) | 5-Hour Bleeding Rate (mL/kg/h) | 6-Hour Bleeding Rate (mL/kg/h) | 7-Hour Bleeding Rate (mL/kg/h) |
|---|---|---|---|---|---|---|---|
| Group 1A (n = 11) | 1.88 ± 4.07 | 3.34 ± 3.78 | 5.15 ± 3.57 | 4.32 ± 2.92 | 5.90 ± 3.0 | 5.56 ± 3.24 | 6.64 ± 3.26 |
| t statistic | NS | NS | .0056 | .004 | .0007 | .0014 | .0007 |
| Group 1B (n = 11) | 2.25 ± 1.91 | 3.03 ± 2.27 | 2.93 ± 2.6 | 3.52 ± 2.74 | 2.91 ± 2.61 | 1.97 ± 2.98 | 2.99 ± 3.07 |
| t statistic | NS | NS | NS | NS | NS | NS | NS |
| Group 2A (n = 4) | 6.52 ± 12.47 | 7.53 ± 10.87 | 8.81 ± 12.6 | 7.39 ± 12.1 | 8.14 ± 19.7 | 5.23 ± 20.0 | 4.51 ± 27.4 |
| t statistic | NS | NS | NS | NS | NS | NS | NS |
| Group 2B (n = 4) | .06 ± .29 | .45 ± .67 | .41 ± .68 | .48 ± .58 | .57 ± .58 | .71 ± .59 | .45 ± .68 |
| t statistic | NS | NS | NS | NS | NS | NS | NS |
Group 1A, rFVIIa, <30 kg; group 2A, rFVIIa, >30 kg; group B, no rFVIIa, <30 kg; group 2B, no rFVIIa, >30 kg.
Values are mean ± SD. Wilcoxon signed rank test for paired samples p value.
NS, not significant.