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Cytokine plasma concentration by ELISA. Plasma levels of IL-6* (A), IL-8* (B), IL-10 (C), and TNF-α (D) in seven patients undergoing CPB. Data are mean ± SD (error bars). BH, before heparinization; 5 minutes after crossclamping; 60 minutes after crossclamping; End, at the end of CPB, prior to reperfusion. *The level of IL-6 and IL-8 was significantly increased after CPB (p < .05).
