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. 2015 Dec 16;5:18035. doi: 10.1038/srep18035

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(A) Luciferase analysis of indicated mono- or double- mutants in rSTING upon stimulated with CMA. 317–319 indicates that S317-E319 in rSTING was mutated into the corresponding residues P316-D318 in mSTING. (B) CMA binding studies of indicated rSTING mutants by ITC. (C) Luciferase analysis of the residue 230 mutants in hSTING upon indicated stimulation.