Table 1. Characterization of MCO hemodialysis membranes, conventional high-flux and high cut-off membranes, based on dextran sieving experiments before and after blood exposure.
Before blood exposure |
After blood exposure |
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Membrane | MWRO [kDa] | MWCO [kDa] | Pore radius [nm] | MWRO [kDa] | MWCO [kDa] | Pore radius [nm] |
Revaclear | 5.7 ± 0.5 | 32 ± 3 | 3.9 ± 0.1 | 4.4 ± 0.3 | 14.2 ± 0.2 | 2.68 ± 0.02 |
MCO 1 | 9.4 ± 0.2 | 56 ± 3 | 5.0 ± 0.1 | 5.0 ± 0.4 | 18.1 ± 0.8 | 3.0 ± 0.1 |
MCO 2 | 10.0 ± 0.6 | 64 ± 3 | 5.4 ± 0.1 | 5.84 ± 0.09 | 18.2 ± 0.3 | 3.0 ± 0.1 |
MCO 3 | 11.3 ± 0.4 | 81 ± 9 | 6.0 ± 0.3 | 6.32 ± 0.06 | 22.7 ± 0.8 | 3.3 ± 0.1 |
MCO 4a | 12.1 ± 0.7 | 99 ± 7 | 6.5 ± 0.2 | 6.77 ± 0.06 | 25 ± 5 | 3.5 ± 0.3 |
Theralite | 15 ± 1 | 300 ± 100 | 10 ± 2 | 8.1 ± 0.8 | 40 ± 8 | 4.3 ± 0.4 |
Values are average ± standard deviation for n = 3.
aExperiments for MCO 4 included also one dextran fraction of 150 kDa.