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. 2015 Dec 16;5:18448. doi: 10.1038/srep18448

Table 3. Hydrodynamic radius (Rh) for albumin and some representative middle and large uremic toxins.

Molecule Rh [nm] Comments Ref.  
β2 microglobulin 1.7 calculated from the diffusion coefficient in free solution 16  
Tumor necrosis factor (TNFα) 1.9 − 2.3 depending on its aggregation state, influenced by concentration and pH 17  
Free light chains (FLC) monomeric state (mostly κ-FLC) 2.3 Stokes’ radius determined by chromatography 18  
Free light chains (FLC) dimeric form (mostly λ-FLC) 2.8 Stokes’ radius determined by chromatography 18  
Albumin 3.51 calculated from the intrinsic viscosity (agrees with Stokes’ radii from diffusion and sedimentation coefficient) 19