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. Author manuscript; available in PMC: 2015 Dec 16.
Published in final edited form as: Cell Rep. 2015 Nov 19;13(9):1868–1880. doi: 10.1016/j.celrep.2015.10.043

Figure 6. Speed of metabolic cycling in yeast is linked to cyclical gene expression.

Figure 6

(A) Differential nutrient content leads to either slow (low glucose) or fast (high glucose) metabolic cycling in yeast. (B) Individual genes show differential periodic expression patterns within the low and high glucose conditions. Expression of YBR284W is only cyclical in the high glucose condition while YLR069C is cyclically expressed under both conditions. AMP indicates amplitude values. (C) Expression pattern of cycling genes in the low and high glucose conditions across the time points sampled. Red, high expression; blue, low expression. (D) More cycling genes are observed in the high compared to the low glucose condition. Left, p < 0.05; right, p < 0.01. At both significance levels, more than 3,000 genes have periodic expression in the high glucose condition. (E) Expression pattern of all genes in the low and high glucose conditions. Red, high expression; blue, low expression. Genes were phase adjusted and ranked by P values. See also Figure S4 and S7.