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. 2015 Dec 6;6:248. doi: 10.1186/s13287-015-0237-4

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© Perea-Gil et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Milestones in the history of natural scaffolds in cardiac tissue engineering for myocardial infarction treatment. Boxes with a grey outline refer to natural scaffolds used in vitro. Boxes with a red outline indicate in vivo highlights related to natural scaffold application. CM cardiomyocyte, ECM extracellular matrix, ESC embryonic stem cell, iPSC induced pluripotent stem cell, MI myocardial infarction