Table 2. OR for myopia and high myopia in UK biobank participants by birth order after adjusting for highest educational qualification.
| Model 1a |
Model 2b |
|||||
|---|---|---|---|---|---|---|
| OR | 95%CI | P | OR | 95%CI | P | |
| MYOPIA (N=89,120) | ||||||
| First vs. second born | 1.12 | (1.08 to 1.16) | 1.40E-11 | 1.09 | (1.05 to 1.12) | 1.30E-06 |
| First vs. third born | 1.18 | (1.12 to 1.23) | 4.30E-12 | 1.10 | (1.05 to 1.15) | 1.20E-04 |
| First vs. fourth born or higher | 1.38 | (1.31 to 1.46) | 6.00E-34 | 1.17 | (1.11 to 1.23) | 1.70E-08 |
| HIGH MYOPIA (N=65,500 c ) | ||||||
| First vs. second born | 1.21 | (1.11 to 1.30) | 3.60E-06 | 1.15 | (1.06 to 1.25) | 4.60E-04 |
| First vs. third born | 1.29 | (1.15 to 1.44) | 6.40E-06 | 1.16 | (1.04 to 1.30) | 7.90E-03 |
| First vs. fourth born or higher | 1.44 | (1.27 to 1.64) | 1.50E-08 | 1.13 | (1.00 to 1.29) | 5.50E-02 |
a
Model 1; Adjusted for age and sex only.
b
Model 2; Adjusted for age, sex and highest educational qualification.
c
Sample size reduced since participants with mild/moderate myopia were excluded.