Table 2.

In vitro IC₅₀ values (µM) of compounds 1 and 2

Test compounds	Sensitive strains		Resistant strains		RI	P value
	3D7	D10	K1	Dd2
1	0.064 ± 0.02	0.047 ± 0.01	0.505 ± 0.10	0.463 ± 0.12	10.7	0.343
2	0.041 ± 0.02	0.122 ± 0.03	0.089 ± 0.01	0.076 ± 0.01	2.2	1
Chloroquine	0.019 ± 0.00	0.023 ± 0.00	0.279 ± 0.002	0.180 ± 0.01	14.4	n/a

The values obtained from antiplasmodial tests represent the mean of three independent experiments each performed in triplicate

RI value, values calculated using the highest CQR IC₅₀ value and lowest CQS IC₅₀ value; n/a, not applicable