Table 1.
Reference | Study typea | n | Blinding | Definition of UD | Confirmation of UD diagnosis | Aim to identify UD risk factors | Comparison according to |
|||||
Sex | Age | Diet | Season | |||||||||
1 | Andrews and colleagues (1994) | C | 18 | Not described | Well described | Histology | Partially | X | X | |||
2 | Bender and colleagues (2008) | B | 81 | Yes (behavioral assessment) | Not defined | Histology | No | X | ||||
3 | Blackwell and colleagues (1995) | B | 266 | Not described | Not defined | Unclear | No | X | X | |||
7 | Dufour and colleagues (2010) | A | 12 | Yes (experiment 1) | Well described | Identification by veterinarian | Partially | X | X | |||
12 | Hampton and colleagues (2012) | C | 25 | Not described | Well described | Histology | Partially | X | X | |||
13 | Kastenmayer and colleagues (2006) | E | 1352 | Not described | Well described | Histology, bacterial culture | Yes | X | X | X | ||
15 | Krugner-Higby and colleagues (2012) | B | 11 | Not described | Well described | Histology, bacterial culture | Partially | X | ||||
19 | Neuhaus and colleagues (2012) | B | 10 | Not described | Partially defined: age and gross findings | Lesion character | Yes | X | ||||
20 | Pugh and colleagues (1999) | B | 75 | Not described | Partially defined: open wounds and excessive scratching | Unclear | No | X | ||||
21 | Sell and colleagues (2000) | B | 31 | Not described | Not defined | Lesion, response to treatment | No | X | ||||
26 | Turturro and colleagues (2002) | B | 56 | Not described | Partially defined: ulceration and self-mutilation | Unclear, possibly histology | No | X | X | X | ||
31 | Zhang and colleagues (2015) | B | 16 | Not described | Partially defined: ulcerated inflammatory lesions | Histology | Partially | X |
Study types: A, blinded, randomized, controlled trial comparing 2 interventions; B, controlled trial lacking either blinding or randomization; C, prospective cohort study; E, retrospective cohort or case-control study