Figure 13.

Effect of VU590 on AeKir and AeKir2B expressed in Xenopus oocytes. Oocytes were bathed in Ringer solution containing 0.5 mM K⁺ (broken line), and 10 mM K⁺ (solid lines) in the absence (black) and presence (red) of VU590 (50 µM). Note the different current scales in A and B. VU590 inhibits AeKir1 (A) but has no effect on AeKir2B (B). Data adapted from Rouhier et al.⁵⁴