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A more complete equivalent circuit of DVC-ICM system. CS1 and CS2 represent the capacitance of the patch clamp pipets glass wall. RL1 and RL2 are the “gigaohm seal” resistances at the sealed spaces between patch pipets and cell membranes. The cell membrane capacitances are indicated with Cma1, Cma2 (for apical membrane) and Cmb1, Cmb2 (for basolateral membrane).
