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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Biomaterials. 2015 Jun 16;64:33–44. doi: 10.1016/j.biomaterials.2015.06.026

Figure 3.

Figure 3

Effects of genetic or molecular inhibition of Iβ3 subunit. PTHrP and Gli2 mRNA are significantly reduced when Iβ3 subunit is knocked down with a targeted shRNA for integrin-β3 (A, D), the integrin specific antibody, LM609 (B, E), or an RGD-mimicking peptide Cilengitide (C, F) in normal serum media (* p<0.05, ** p<0.01, *** p<0.005). N=3 biological replicates. Data presented as fold change over MDA-MB-231 ctrl.