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. 2015 Nov 20;1(10):e1500775. doi: 10.1126/sciadv.1500775

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Copyright © 2015, The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

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Fig. 3 — Brain graph showing the network connectivity of nodes (blue spheres) via edges (lines, color-coded for their Z score), indicating the strength of the connections. (A to D) fMRI measurements under light isoflurane anesthesia revealed a reduced functional connectivity between a number of neocortical brain areas in the Fmr1^−/y (A and B; n = 7) compared to WT (C and D; n = 10) mice. In particular, the intrahemispheric connections are strongly affected (A and C), whereas the homotopic interhemispheric connectivity is only partially affected (for example, Mo-Mo; B and D). HC, hippocampus; Mo, motor cortex; S1, primary somatosensory cortex; V1, primary visual cortex; CPu, caudate putamen.